Contributions for the 20th Discussions in Structural Molecular Biology

Updated on February 21, 19:15

C. Bařinka
Structure-function studies of polyglutamylase TTLL-11

J. Benýšek
Novel inhibitors of the methyltransferase METTL3-METTL14 complex

J. Beránek
Alphafold-driven coarse grained dynamics

L. Biedermannová
Comparative Analysis of DNA and RNA Hydration Patterns: Insights from Crystallographic Data

A. Bitala
Biophysical and binding characterization of rhesus CMV UL144 as a promising modulator of the T-lymphocyte CD160 pathways

E. Bouřa
Viral RNA-methyltransferases: function, structure and inhibition

T. Brom
Rta - Replication and transcription activator of Epstein-Barr virus: functional and structural implications for novel antiviral strategy

O. Bulvas
Revealing the function of the C-terminal part of mycobacterial inosine-5′-monophosphate dehydrogenase

L. Bumba
A multifaceted role of filamentous hemagglutinin (FHA) in the virulence of pathogenic Bordetella species

O. Cehlár
Insights into the Alzheimer's disease specific pre-aggregation conformation of monomeric tau proteins using DC11 antibody

T. Charnavets
Biophysical techniques at Centre of molecular structure of BIOCEV

P. Chrupková
The Role of Carotenoid Excited State in Orange Carotenoid Protein Activation

Z. Cieniková
The role of semi-disordered scaffold proteins in phage LUZ19 procapsid assembly

J. Cikhart
Computer simulations of the bacterial ribosome using coarse-grained models

R. Crha
Combining of hybrid QM/MM simulations with machine learned potentials

E.A Curtis
A fluorescent deoxyribozyme for high-throughput screening

M. Černý
Tale of tails; structural comparison of the RNA polymerase δ-subunits

M. Čížková
Deciphering the role of BscX and BscY subunits in the Bordetella Type 3 Secretion System

G. Demo
Distinct 30S subunit dimerization architecture facilitated by a novel ribosome dimerization factor in archaea

A. Dikunová
Assembly of torpedo termination complexes in thermophilic and mesophilic organisms

V. Duchoslav
Unlocking STING's defenses: fluorinated cyclic dinucleotides resistant to viral poxins revealed by crystallography

T. Füzik
Asymmetric reconstructions of immature Tick-borne encephalitis virus particles reveal assembly mechanism of flaviviruses

A. Gardiner
Cryo-EM structure of the large photosynthetic complex from two species of Gemmatimonadota

M. Gondová (no link)
Use of a “helper protein” to improve cryo-EM reconstructions – a case of La Jolla and Motts Mill viruses

M. Gopalswamy
Structural biology of Acute Myeloid Leukemia (AML) protein and small molecule inhibitor complex

T. Greňa
Structural characterisation of tau protein filaments

L. Gryčová
Fluctuations in metabolic content affect the integrity of tau envelopes

Z. Hlavenková
The structure of bacteriophage phi9224

J. Houser
Protein-protein interaction analysis in education – A model case of chymotrypsin inhibitor

A. Hrádková
Structural variability of peptide deformylase

D. Hrebík
High-resolution in situ structures of HIV-1 matrix protein by single particle analysis

A. Hušková
Enzymatic Revelations of Abasic Site Interstrand Crosslinks repair facilitated by NEIL3

M. Janošev
Calcium-mediated regulation of the human ubiquitin ligase Nedd4-2

L. Kašiárová
Towards unlocking the potential of staphylokinase for ischemic stroke treatment via a structure-based protein engineering

V. Klápšťová
Structural characterization of the interaction between BRCA1-BARD1 and RNA polymerase II

M. Kloz
Multiple Retinal Isomerizations during the Early Phase of the Bestrhodopsin Photoreaction

M. Koblížek
Cold-loving bacterium from a mountain lake harvests light energy using both bacteriochlorophyll-containing photosyntems as well as proton-pumping rhodopsins

M. H. Kolář
Three epochs of nascent protein translocation through the ribosome exit tunnel

M. Kopecký
Leica optic microscopy - product and application view

D. Košek
Structural insight into domain architecture and regulation of Nedd4-2 E3 ubiquitin ligase

T. Kouba
RNA polymerase recycling by mycobacterial HelD: an alternative, HelD-protected pathway of transcription initiation

A. Kozeleková
How does phosphorylation affect interaction between 14-3-3ζ and Tau proteins?

I. Kratochvílová
Study of the relationship between embryo quality, speed of development and clinical pregnancy in PGT cycles

K. Krejčová
Elucidation of enzymatic mechanisms and structure of Ntaya NS5 enzyme

I. Křenková
e-INFRA CZ Interactive and FAIR: Beyond Qsub Computing

S. Kurupath Bhavadas
Resolving protein dynamics with Stokes and anti-Stokes Raman correlation microscopy

B. Landová
NEIL3-ssDNA Structure Insights into Repairing Abasic Site Interstrand Crosslinks

S. Macháček
Towards the structure of stearoyl-acyl carrier protein complex with fatty acyl

L. Martínek
Characterization of de novo missense variants in individuals with neurodevelopment disorders and their impact on the structure and function of the protein SHP2

K. Monková
Structural investigation of the 40S particle

J. Moravcová
Preparation of biological samples for cryo-electron microscopy using the HPF "Waffle" method

L. Motlová
Structural characterization of selective HDAC6 inhibitor Marbostat-100 with improved stability

L. Mukhamedova
Resolving the early infection stages of the viruses from the order Picornavirales in vivo

S. Narasimhan
Structural characterization of novel binding partner of mycobacterial transcription initiation factor sigma-A

H. Nedozrálová
Visualization of tau pathology using in situ cryo-ET

I. Nemčovičová
Mutational analysis on viral HCMV UL141 protein to specify the binding site of novel antagonist that blocks TRAIL-R2 binding

L. Nepovímová
Visualising Enterovirus 71 Genome Replication In Situ

Z. Nováková
Evolutionary study of histone deacetylase 11

M. Novotná
Clincelin – our new weapon to combat antibiotic-resistant bacterial pathogens

M. Padilla Blanco
Mimicking viral evolution by yeast surface display to predict new coronavirus-related pandemics

J. Patryn
Bio-Rad: out of complexity, find the simplicity

J. Pavlíček
Core Facility Devoted to Crystallization of Proteins and Nucleic Acids, Centre of Molecular Structure, IBT CAS

E. Pirnosová
The comparison of 14-3-3 homo- and heterodimers kinetics

P. Plevka
Structure and replication cycle of a virus infecting climate-modulating alga Emiliania huxleyi

A. Polák
Production of monoclonal antibodies and their co-crystallization with intrinsically disordered protein tau

M. Polák
Plum Pox Virus structure and basis for structural variability of its virus-like particles

E. Pyrihová
Protein Production facility at the Centre of Molecular Structure

K. Radilová
Structural characterization of influenza A polymerase PA subunit domains in complex with novel inhibitors

K. Ray
Assessment of sample quality with every measurement FIDA-1 Fundamentals

B. Schneider
First twenty years of Discussions in Structural Molecular Biology

T. Skálová
Solving X-ray structure at low resolution: Natural killer cell receptor NKp30 with its tumor ligand B7-H6

K. Skubnik
Cryo-EM Reveals RECQ5's Regulatory Role in RNAPII-Mediated Transcription

G. Soares Guerra
Unveiling the coupling of transcription and translation in bacteria

Š. Sobotková
Cryo-EM Reveals the Structure and Infection Mechanism of Phage LUZ19

V. Spiwok
Analysis and acceleration of molecular simulations by time-lagged tSNE

J. Srogoň
New complexes of the bacterial transcription system

J. Stránský
CF Diffraction Techniques in Centre of Molecular Structure: Employing high-end X-ray technologies for laboratory structural biology

M. Suchý
Molecular dynamics simulations of single amino-acid substitution in BRAF:MEK1 complex

M. Šiborová
Structural basis for postfusion-specific binding to Respiratory Syncytial Virus F protein by the antigenic site-I antibody 131-2a

J. Šilhan
Exploring the Structures of the 20S Proteasome and Their Small Molecule Inhibitors Using Cryo-EM

P. Škvára
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39

K. Šnajdarová
X-ray structures of (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum reveal a new mode of homodimerization that is atypical for this enzyme family

H. Šváchová
Cryogenic Electron Microscopy Core Facility at IOCB Prague

G. Tedeschi
Analysis and Sampling of Molecular Simulation with extended Autoencoder architectures

R. Vácha
New Scramblases with Moonlighting Functions Identified in Mitochondria

O. Vaněk
Structural immunology of (super)natural killer cell receptor-ligand recognition

P. Vaňková
Mass spectrometry as a tool for protein structure analysis

M. Vaško
Insights into Molecular Interactions between nsp14 and nsp10 in SARS-CoV-2 Replication

Y.Yurenko
Accurate Multi-Scale Computations of Binding Free Energies in Insulin/Insulin Receptor Complex

J. Zahradník
Dual Perspectives on the Evolution of SARS-CoV-2 Receptor Binding Domain

J. Zemaník
QM/MM Reaction Simulations of Alpha-(1,3)-fucosyltransferase of Helicobacter pylori