24th Heart of Europe Bio-Crystallography Meeting


Plenary Lecture





Prof. Dr. Rolf Hilgenfeld

German Center for Infection Research, Germany

Rolf Hilgenfeld studied chemistry at the University of Göttingen (Diploma 1981), where he conducted research at the Max Planck Institute for Biophysical Chemistry. PhD he obtained at the Free University of Berlin for the determination of the structure of a plant protease. He then worked on proteosynthesis in the Hoechst laboratory. In 1995 he was appointed professor for biochemical structural research at the University of Jena and in 2003 he moved to the chair for biochemistry at the University of Lübeck. He worked on proteases in HIV and since 1998 on coronaviruses. He published the three-dimensional structure of the SARS virus protease. At the beginning of 2020 he and his colleagues succeeded in elucidating the three-dimensional structure of the main protease Mpro of SARS-CoV-2 and suggested its inhibitor.