MS details

The schedule is available at https://www.conftool.com/iucr2020/

Fragment Screening, LCP, and Automation

Comments

The increasing speed of detectors and the ever increasing automation and beam intensities at synchrotrons have made it possible to collect several hundred diffraction data sets within 24 hours of beam time. This had made extensive screening-by-crystallography experiments feasible. Fragments can be screened for binding in early-stage drug discovery approaches, metabilites can be screened for functional investigations, etc. Such experiments also require a different way of thinking about individual diffraction data sets. In a screening campaign consisting of several hundred data sets, the individual data sets are essentially meaningless. The power of such an experiments lies in the simultaneous analysis of all data sets at once.

Chair persons

Name

Family

Institution

City

Country

Region

Lisa

Keefe

Argonne National Laboratory

Argonne

USA

ACA

Alice

Douangamath

Diamond Light Source Ltd

Oxfordshire

UK

ECA

 

Invited speakers

Name

Family

Institution

City

Country

Title

Stephen M.

Soisson

Merck & Co.

West Point, PA

USA

Martin

Noble

University of Newcastle upon Tyne

Newcastle

UK