Over the past decades, X-ray diffraction of biological samples, also called macromolecular crystallography (MX) has been developed to the most powerful method to gain insights into the 3d structural space of biological macromolecules, like protein, protein-protein and other complexes. One key for these advances is the use of highly brilliant X-rays produced by electron storage rings to investigate crystals of large unit cells or micrometer sized crystals.
Within this presentation, an overview of this technique and its current applications are provided.