The Centre of Molecular Structure offers wide range of methods of structural biology. It operates in BIOCEV as part of Institute of Biotechnology, AS CR. CMS consists of facilities devoted to crystallization of macromolecules, X-ray diffraction, biophysical characterization and advanced mass spectrometry. Services are provided via Czech Infrastructure for Integrative Structural Biology (CIISB) and Instruct. The latest improvements of our instrument portfolio are SAXS Point 2.0 for small angle X-ray scattering studies of biomolecules in solution, MALDI TOF mass spectrometer, excimer laser for induced protein modification, and newly equipped room for spectroscopy.
CIISB research infrastructure project LM2015043 funded by MEYS CR is gratefully acknowledge for the financial support of the measurements at the CMS.