Protein crystallization projects at the Faculty of Science of the USB CB

Ivana Kuta Smatanova

University of South Bohemia in Ceske Budejovice, Faculty of Science, Branisovska 31, 370 05 Ceske Budejovice, Czech Republic and Academy of Sciences of the Czech Republic, Institute of Nanobiology and Structural Biology GCRC, Zamek 136, 373 33 Nove Hrady, Czech Republic

The protein crystallography is one of the methods used to study the protein structures and to describe their function and mechanism. The most important and necessary condition to used protein crystallography is obtaining of well-diffractable monocrystals. Different crystallization techniques such as standard, advanced and alternative methods are used to crystallize soluble and membrane proteins and protein complexes. Research projects are designed for graduate students and postgraduates who work on these projects on different levels. Finally developed methods and obtained crystallization and crystallographic data are compiled and results are published in scientific journals.

This research is supported by the GACR (P207/12/0775 and P207/11/0717) and by the AS CR.