Getting the best data from your crystal

Vernon Smith^a, Marianna Biadene^a and Matthew Benning^b

^aBruker AXS GmbH, Karlsruhe, Germany, ^bBruker AXS, Madison, WI, USA.
E-mail: vernon.smith@bruker-axs.de

Macromolecular crystallography typically involves trying to get the best possible data from crystals that are rarely as well diffracting as we would like. In order to do this, careful planning and execution of the diffraction experiment can make the difference between measuring almost no reflections and collecting a data set suitable for structure determination.

This talk will briefly introduce how good sample mounting, using the best data collection strategy and optimising the instrument configuration can contribute to getting the best data from poor crystals