Transcription termination of nonpolyadenylated transcripts

 

F. Hóbor1, H. Cerna1, V. Bacikova1, J. Pasulka1, K. Kubicek2, R. Stefl1

 

1National Centre for Biomolecular Research, Faculty of Science, Masaryk University, 625 00 Brno

2Dept. of Condensed Matter Physics, Faculty of Science, Masaryk University, 61137 Brno

stefl@chemi.muni.cz

 

 

RNA polymerases produce RNA transcripts by initiating and terminating transcription in response to specific sequence elements. Signals that terminate transcription reside either in the DNA template sequence or, alternatively, in the nascent RNA transcript. We will present our functional and structural data related to transcription termination of nonpolyadenylated transcripts that is mediated by the Nrd1 complex.