Structure and dynamics of RNA and DNA. Advanced computational studies

J. Šponer

¹Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 612 65 Brno, Czech Republic

sponer@ncbr.chemi.muni.cz

Modern computational approaches represent a useful tool to study selected aspects of structure and dynamics of nucleic acids. I will present a short survey of the latest developments in the field, with a special emphasize given to molecular dynamics studies of RNA and DNA. Basic principles, main advantages and substantial limitations/failures will be explained.