Structure and dynamics of RNA and DNA. Advanced computational studies


 J. Šponer


1Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 612 65 Brno, Czech Republic


Modern computational approaches represent a useful tool to study selected aspects of structure and dynamics of nucleic acids. I will present a short survey of the latest developments in the field, with a special emphasize given to molecular dynamics studies of RNA and DNA. Basic principles, main advantages and substantial limitations/failures will be explained.