October 10
10:00-10:20 Cristales: a world to discover, opening of exhibition by dean/vice-rector and dr. Pavlína Řezáčová from Institute of organic chemistry and biochemistry and Institute of Molecular Genetics Praha
10:20-11:20 Structure-based drug design (habilitation lecture)
(Pavlína Řezáčová)
11:20-11:45 Protein engineering
(Radka Chaloupková)
11:45-12:10 How the cell knows where to divide?
(Imrich Barák)
12:10-12:35 Structural basis for pharmacological reactivation of p53 tumorigenic mutants
(Oksana Degtjarik)
12:35-13:00 Crystallization experiences and adjustment of crystal size for different Xtall experiments (serial PX, XFEL, etc.)
(Iosifina Sarrou)
13:00-14:00 Lunch break
14:00-14:25 Structural analysis of macromolecular complexes by single-particle cryo-electron microscopy
(Iulia Iermak)
14:25-14:50 Application of cryo-electron tomography to study functions of protein complexes
(Matthias Pöge)
14:50-15:15 Cell shape formation controlled by cytoskeleton
(Naoko Mizuno)
15:15-15:45 Coffee break
15:45-16:10 Dual-mode recognition of DNA substrates by Holliday junction resolvase GEN1 - a biochemical, biophysical ans structural analysis
(Christian Biertuempfel)
16:10-16:35 Bioinformatic analysis of CE16 acetylesterases
(Ľubica Urbániková)
16:35-17:00 Phase separation and formation of membrane-less organelles in cells
(Roman Tůma)
17:00-17:25 Nanostructured surfaces for advanced biomedical applications
(Vít Straňák)
17:25-17:50 Introduction to NanoTemper Solutions for Structural Biology
(Pawel Kania)
17:50-18:00 25th IUCr congress in 2020 in Prague
(Radomír Kužel)
18:00-18:10 Discussion and closing remarks
18:30 Dinner
October 11
NanoTemper MST & nanoDSF Workshop
09:00-09:30 Seminar: Interaction analysis with MicroScale Thermophoresis (MST)
(Malgorzata Poczopko, NanoTemper Technologies)
09:30-10:00 Protein stability and quality measurements with nanoDSF
(Pawel Kania, NanoTemper Technologies)
10:00-10:30 Coffee break and networking session
10:30-13:00 Hands-on session (MST and nanoDSF)
13:00-14:00 Lunch break
14:00-17:00 Hands-on session (MST and nanoDSF)