Proteins and Drug Design

Oral Contributions

1. Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors
   B.A. Katz, J.M. Clark, J.S. Finer-Moore, T.E. Jenkins, C.R. Johnson, M.J. Ross, C. Luong, W.R. Moore, R. Stroud

2. Crystal Structures of the Catalytic Domain of HIV-1 Integrase Free and Complexed with its Metal Cofactor: High Similarity of the Active Site with Other Viral Integrases
   S. Maignan, J.P. Guilloteau, Qing Zhou-Liu, C. Clement-Mella, V. Mikol

3. Drug Design and Resistance Mutants in HIV Reverse Transcriptase
   D. Stammers

4. Cell Cycle Inhibition and Drug Design: Crystal Structures of cdk2-inhibitor Complexes
   M. Noble, N. Brown, J. Endicott, L. Johnson, A. Lawrie, J. Tucker, P. Tunnah, A. Calvert, N. Curtin, B. Golding, R. Griffin, D. Newell

5. Crystal Structure of the Biosenzor Glucose Dehydrogenase
   A. Oubrie, H. Rozeboom, K. Kalk, B. Dijkstra

6. Prolyl oligopeptidase: a beta-propellor regulates cytosolic proteolysis
   V. Fülöp

7. Controlling insulin bioavailability by crystal contact engineering
   R. Hilgenfeld, T. Sicker, M. Dörschug, R. Obermeier, K. Geisen, G. Seipke, H. Berchtold

Posters

1. Structural Studies of Eye-Lense Crystallins.
   A.K. Basak, G. Wright, C. Slingsby

2. Non-Proline CIS Peptide Bonds in Proteins
   M.S. Weiss, A. Jabs, R. Hilgenfeld

3. Neutron Crystallographic Evidence of Lipase/Colipase Complex Activation by a Micelle
   J. Hermoso, D. Pignol, S. Penel, M. Roth, C. Chapus, J.C. Fontecilla-Camps

4. Crystal Structures of Some Prolyl-Oligopeptidase - Inhibitor Complexes
   V. Harmat, Zs. Böcskei, V. Fülöp, K. Kánai, G. Náray-Szabó, I. Hermecz, L. Polgár, P. Arányi

5. Contribution of Rnase Sa Complexes to Protein-Protein/Nucleic Acid Recognition
   L. Urbanikova, J. Sevcik

6. Structural parameters for Proteins Derived from the Atomic Resolution (1.09A) Structure of Designed Variant of the ColE1 Rop Protein
   M. Vlassi, M. Kokkinidis

7. Structure of the Glycosylated Plant Aspartic Proteinase Cardosin A, to 1.72 A Resolution
   I. Bento, C. Frazao, R. Coelho, J. Costa, C. Faro, P. Verissimo, E. Pires, J. Cooper, Z. Dauter, K. Wilson, M.A. Carrondo

8. CAMM of Anticancer Drugs
   K. Huml, V. Šubr, K. Ulbrich

9. Structure-Function Studies of Human Ceruloplasmin
   V. Zaitsev, I. Zaitseva, G. Card, P. Lindley

10. Structure of Chitinase from Jack Bean
    M. Hahn, M. Hennig, B. Schlesier, W. Höhne

11. Protein Tiration in the Crystal State
    R. Berisio, V.S. Lamzin, F. Sica, K.S. Wilson, A. Zagari, L. Mazzarella

12. Substrate Complexes of the free radical enzyme Galactose oxidase
    E. Vinecombe, S.E.V. Philips

13. The Crystal Structure of Human Glutathione Reductase Inhibited by Ajoene
    S. Bonse, H. Gallwitz, A. Martinez, I. Schlichting, R.L. Krauth-Siegel

14. A Five-Residue Deletion Alters the Folding and Increases Drastically the Stability of ROP
    M. Kokkinidis, G. Cesareni, H.-J. Hinz, Y. Papanikolau, M. Vlassi

15. Structural Studies of Penicillin binding proteins
    E. Gordon, N. Mouz, E. Duee, O. Dideberg

16. The structure of three inhibitors in complex with HIV-1 protease reveals the importance of structural waters
    H.O. Andersson, J. Hulten, S. Löwgren, N.M. Bonham, W. Schaal, A. Karlen, A. Hallberg, T. Unge

17. Structural studies of purple acid phosphatase from rat bone.
    Jia Jia, E. Johansson, H. Kaija, P. Vihko, G. Schneider, Y. Lindqvist

18. The Structure of Pore-Forming Proteins in Prokaryotes and Eurokaryotes
    K. Zeth, J. Diez, M. Dolder, V. Adams, K. Diederichs, W. Welte, T. Wallimann, H. Engelhardt

19. Crystal Structure of Pneumocystis Carinii Dihydrofolate Reductase Cofactor Complex with Tab, a Potent, PC-Selective Antifolate
    N. Galitsky, V. Cody, D. rak, J.R. Luft, W. Pangborn, S.F. Queener, M.F.G. Stevens, C. Laughton, D. Chan

20. Crystal Structure of S58A Mutant of E. coli L-Asparaginase II
    M. Kozak, M. Jaskolski

21. Studies of Papain in Complex with Epoxysuccinyl-peptide Inhibitor
    M. Kozak, E. Jankowska, J. Ciarkowski, Z. Grzonka, M. Jaskolski

22. The crystal structure of beta-ketoacyl [ACP] synthase I from Escherichia coli
    J.G. Olsen, A. Kadziola, P. von Wettstein-Knowles, S. Larsen

23. Crystallographic Studies of Mammaian Pentraxins
    D. Thompson, M.B. Pepys, S.P. Wood

24. The use of X-ray crystal structures in the design of novel, potent thrombin inhibitors.
    A. Cleasby, H. Jhotti, S. Patel, A. Wonacott, M. Weir

25. High Resolution Crystal Structure of a Histamine-Binding Rhipicephalus Appendiculatus
    P. Adams, G.C. Paesen, K. Harlso, P.A. Nutta, D.I. Stuart

26. Crystals of FAB+hCG complex and fabs.
    M.A. Dingwall, N.W. Isaacs

27. Anti-Retroviral Drug Design Based on Structure Analysis of Proteases
    J. Hasek, J. Dohnalek, J. Duskova, J. Konvalinka, M. Hradilek, M. Soucek, J. Sedlacek, J. Brynda, E. Buchtelova