SAPS-DB: A DATABASE ON THE STRUCTURAL ASPECTS OF PROTEIN SYNTHESIS

S. Al-Karadaghi, S. Liljas

Dept. of Molecular Biophysics, Lund University, P.O.Box 124, 221 00 Lund, Salam.Al-Karadaghi@mbfys.lu.se

In the past few years significant progress has been made in the structural analysis of ribosomal components and translational regulatory factors. The growing amount of information necessitates its organisation in a way easily available for scientist active in the field of protein synthesis or in related fields. We have undertaking the task of creating a database dedicated to various structural aspects of protein synthesis (SAPS). The database is easily accessible through the Internet and includes information on amino acid sequences and three-dimensional structure of ribosomal proteins and translation factors, their binding sites on the ribosome, possible mutations and their relation to antibiotics resistance, links to other related databases. The database can be accessed through http://www.mbfys.lu.se.