PROTEIN CRYSTAL STRUCTURES FROM POWDER DIFFRACTION DATA

R.B. Von Dreele

Lujan Center, Los Alamos National Laboratory, Los Alamos, NM, 87545 USA

Keywords: Protein, powder diffraction, Rietveld refinement

Recent advances in the measurement and analysis of powder diffraction data have progressed to the point where it may be fruitful to consider the possibility of examining the crystal structures of proteins using this technique. Through the use of simulation techniques and real data, this talk will explore the feasibility of Rietveld refinement of protein crystal structures with synchrotron X-ray powder diffraction data. The possibility of solving these structures will also be explored.